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By the command of His Majesty Sultan Haji Hassanal Bolkiah Mu'izzaddin Waddaulah ibni Al-Marhum Sultan Haji Omar 'Ali Saifuddien Sa'adul Khairi Waddien, the Sultan and Yang Di-Pertuan of Brunei Darussalam, Pg Dr Haji Mohd Esa Al-Islam bin Pg Haji Mohd Yunus was appointed as Deputy Permanent Secretary, Ministry of Defence on 13 April 2020.  

Prior to his appointment as Deputy Permanent Secretary, Pg Dr Haji Mohd Esa Al-Islam bin Pg Haji Mohd Yunus joined the Ministry of Defence as the Director of Centre of Science and Technology Research and Development (CSTRAD) on 13 June 2017.

He started his career in Universiti Teknologi Brunei (UTB) in 1993 as a lecturer. His research interests are in creative engineering design and management, and manufacturing systems and engineering. He previously led consultancy and corporate social responsibility works for private and public sectors. In 2002, he received Silver Award for Civil Service Award under UTB’s Material Testing Project.

He was an Assistant Teacher in Faculty of Engineering and the Environment, University of Southampton; supervised Internship Student from Japan during his PhD from 2005 to 2008; a facilitator for HRM V Sigma, teaching on “Creative techniques and Tools”, ILIA, UBD, 2009 where he was also appointed as Deputy Dean for Postgraduate Studies and Research in the same year. In 2011, he was appointed as Deputy Dean of Faculty of Engineering; promoted as Dean for Faculty of Engineering in 2012; appointed as Assistant Vice Chancellor for Academic (AVCA) in 2013; appointed as Professional Board member for Architects, Professional Engineers and Quantity Surveyors (APEQS), at the Ministry of Development, Brunei Darussalam in 2014 - 2018; Assistant Vice Chancellor for Industry and Services (AVCIS) in 2016 and Senior Assistant Professor (SAP) for Engineering in April 2016. He was also the Chairman of SEAMEO VOCTECH Governing Board in 2013-2017. 

With the consent of His Majesty the Sultan and Yang Di-Pertuan of Negara Brunei Darussalam, he received Pingat Indah Kerja Baik (P.I.K.B) and The Most Blessed Order of Setia Negara Brunei 4th Class (P.S.B) in 2006 and 2013 respectively. 

He graduated from University of Westminster, UK with Bachelor of Engineering in Mechanical Engineering in 1993 and did his PhD on Engineering Sciences at University of Southampton, UK in 2009. In 2014, he completed a one month course on Senior Management Programme (SMP2014), at Lee Kuan Yew, School of Public Policy, National University of Singapore (NUS), Singapore. 
Pg Dr Haji Mohd Esa is married to Dr Hjh Noor Maya binti Haji Mohd Salleh with three children. His interests includes hiking, cycling and reading.